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The ability to “see” single biomolecules with laser microscopy has led to a revolution in research opportunities for chemistry, physics, and molecular biology.

In this next edition of LIVE@Frost Science on Thursday, March 30, Dr. David J. Nesbitt of JILA, University of Colorado, will present A Brief Stroll through the World of Single Molecule Microscopy: How to Study Biology, One Molecule at a Time. Dr. Nesbitt will kick off his presentation with interactive experiments that illustrate the science of cooking and involve hands-on audience participation.

After the demonstrations, this talk will include a few stories on how we can use modern laboratory techniques to measure the folding of DNA, RNA in real time. This folding is what allows long strands of DNA and RNA to fit inside our cells. Dr. Nesbitt will discuss the effect of heating and cooling or adding other compounds on the folding of DNA and RNA, and why this is important. These stories reveal the development of simple physical pictures that help us interpret, explain and potentially influence the process of DNA and RNA folding at the single molecule level.

LIVE@Frost Science: The World of Single Molecule Microscopy is presented in partnership with Florida International University (FIU) with support by the National Science Foundation (NSF).

Admission is complimentary. Tickets are limited to four per transaction. Program will take place inside the Power of Science exhibition in the Ocean Gallery.

Doors open at 6:30 p.m. Program starts promptly at 7:00 p.m. Seating is first-come, first-served.

Food and beverage will be available for purchase prior to the event.

Please note registration to the event does not include museum admission. Museum exhibitions close at 6:00 p.m. Onsite parking is available in the museum garage for $8 flat rate starting at 6:00 p.m.

Professor David Nesbitt

Professor David Nesbitt is a fellow of JILA, a physicist at the National Institute of Standards and Technology (NIST), a Full Professor in both the Department of Chemistry and Biochemistry and in the Department of Physics at the University of Colorado at Boulder.

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